Professor
Charles Armstrong Chair, Department of Epidemiology
MHS, Johns Hopkins School of Hygiene and Public Health, 1975; ScD, Johns Hopkins School of Hygiene and Public Health, 1977
Bloomberg School of Public Health
Epidemiology
Environmental Health Sciences, International Health, Health, Behavior and Society
David Celentano, ScD '77, MHS '75, is Professor and Charles Armstrong Chair of the Department of Epidemiology, with joint appointments in International Health, Health, Society and Behavior and Medicine (School of Medicine). His research integrates behavioral science theory and research with epidemiology, in the study of behavioral and social epidemiology. While originally trained in a chronic disease paradigm (alcoholism and cancer control), he began his research in HIV/AIDS and STDs in the early 1980s. He has worked on some of the major cohort studies (ALIVE, MACS) in HIV epidemiology, as well as conducted intervention research in the USA for heterosexual men and women, injection drug users, and young men who have sex with men. -
He turned to international research in 1990, when he began a long-term collaboration with Chiang Mai University in northern Thailand. He has worked on and directed numerous HIV/AIDS and STD epidemiological investigations and preventive interventions. He and his collaborators have demonstrated that a behavioral intervention with young military conscripts lead to a 7-fold reduction in incident STDs and halved the HIV incidence rate. In addition, the role of STDs and alcohol use on HIV acquisition has been shown. More recently, his group has conducted a prospective study of hormonal contraception in relation to HIV seroconversion, a study with significant family planning policy and health implications. Today, he is the Principal Investigator of four NIH-supported studies in Thailand, focusing on interventions to influence the association between opiate use, methamphetamine use, and other drugs on HIV. The focus of these interventions is to harness indigenous peer networks for risk reduction. Other work addresses the use of antiretrovirals as HIV prevention and opioid substitution therapy as HIV prevention.
epidemiology, international health, HIV, AIDS, STDs, behavior, Asia, HIV/AIDS prevention, Thailand, India, Vietnam
2000 Fellow, American College of Epidemiology -
2002 Member, American Epidemiological Society -
2002 Innovators Award, American Association for Public Opinion Research -
2002 Achievement Award, American Sexually Transmitted Disease Association -
2006 Doctor of Philosopy in Medical Science (honoris causa), Chiang Mai University
Research Projects
A5175: Once-Daily PI + Non-NRTI Regimens for Initial HIV Treatment
This study will compare three combinations of anti-HIV drugs to learn if two different once-daily combinations of anti-HIV drugs work as well as the standard twice-a-day combination of anti-HIV drugs for the initial treatment of individuals infected with HIV-1 who are from diverse areas of the...
Community-Based Vct: Thailand
In this study, Phase III of a community-level randomized controlled study, 32 communities in Africa (Tanzania, Zimbabwe and South Africa) and 14 communities in Thailand will be randomized to either a community-based HIV voluntary counseling and testing (CBVCT) intervention or a clinic-based...
DOT-HAART For HIV-Infected South African Adults
The primary objective of this study is to evaluate the effectiveness and feasibility of directly observed therapy (DOT) using patient-nominated peer supervisors as a strategy to improve adherence to highly active antiretroviral therapy (HAART) in HIV-infected adults in South Africa. This country...
HIV Prevention Trials
Johns Hopkins University has partnered with several different entities within Thailand including Thailand’s Chiang Mai University of Public Health’s Research Institute for Health Sciences [RIHES] and its Faculty of Medicine, HIV Network for Prevention Trials participating medical centers in...
HPTN 052- A Randomized Trial to Evaluate the Effectiveness of Antiretroviral Therapy Plus HIV Primary Care versus HIV Primary Care Alone to Prevent the Sexual Transmission of HIV-1 in Serodiscordant Couples
HPTN 052 is a Phase III, two-arm, multi-site, randomized trial to determine the effectiveness of two treatment strategies in preventing the sexual transmission of HIV in HIV-serodiscordant couples.
Based on data collected in Africa and Thailand, there is a correlation between HIV viral load ...
JHU Southern Asia Clinical Trials Unit
Johns Hopkins University (JHU) and its partners in Thailand and India are pleased to announce the funding of the JHU Southern Asia Clinical Trials Unit, David D. Celentano, Principal Investigator. This CTU is focused on recruiting injecting drug users and other high risk populations severely...
NIMH Collaborative HIV/STD Prevention Trial -- India
The NIMH Collaborative HIV/STD Prevention Trial is a two-arm randomized, community-level trial being conducted in five countries: China, India, Peru, Russia, and Zimbabwe. It is the first international test of a community-level prevention program based on the theory of diffusion of innovations...
Peer and Family-Based Social Support For HIV Treatment Adherence in South Africa
The goal of this study is to understand the role of family or peer support as a tool for improving adherence to antiretroviral therapy in an HIV positive population in the Western Cape Province of South Africa. Data will be collected from a clinical trial evaluating the impact of community-based...
Preventing Rural Thai Methamphetamine Abuse and HIV by Community Mobilization
This revised competing continuation application of R01 DA14702-01 continues our behavioral interventions to reduce adolescent and young adult HIV sexual risks associated with non-injection methamphetamine use in northern Thailand. During the first five years of our grant, we characterized...
Prevention for Positives: A RCT for Vietnamese HIV-positive IDUs
This study is a randomized controlled trial of a multilevel social-behavioral intervention for HIV-positive injecting drug users (IDUs) in Vietnam. Our ongoing NIMH-funded study at the same site found high HIV prevalence (42%) among IDUs. Among HIV-positive IDUs, 64% percent shared injecting...
Reducing Global Inequities in Burden of Disease
The Johns Hopkins University has a long history of engagement with global health issues and has one of the largest programs of its kind in the world. It is an intensely collaborative environment across disciplines, departments, and schools where faculty routinely engage in multidisciplinary...
Southern Asia HIV/AIDS Clinical Trials Unit
Johns Hopkins University and its partners in Thailand and India are pleased to propose the JHU Southern Asia Clinical Trials Unit, David D. Celentano, Principal Investigator. This CTU focuses on recruiting injecting drug users (IDU) and high risk Asian populations affected by the HIV/AIDS...
Structural Interventions for HIV prevention among men in wine shops in Chennai, India
The study seeks to modify the physical and social environment of wine shops, or bars in Chennai. By installing interactive and educational computer and video games in this setting, we hope to educate patrons about HIV and motivate care seeking behaviors. We anticipate that the use of technology...
Structural Interventions for HIV prevention among wine shops in Chennai, India
In the proposed study, we seek to modify the physical and policy environment of the wine shop that will help patrons seek care for HIV/STDs. We aim to use technology to modify the physical environment of the wine shop by placing computers with HIV educational to inform and motivate care seeking....
Support Networks & HAART Adherence among Vulnerable Indian HIV+’s
The proposed study seeks to examine influences of social support network characteristics, informal HIV caregiving relationships, and household factors associated with optimal adherence to HIV medication and medical service use among disadvantaged Indian populations living with HIV /AIDS.
The...
Click here for a full list of Dr. Celentano's publications -
Sutcliffe CG, Aramrattana A, Sherman SG, Sirirojn B, German D, Wongworapat K, Quan VM, Keawvichit R, Celentano DD. Incidence of HIV and sexually transmitted infections and risk factors for acquisition among young methamphetamine users in northern Thailand. Sex Transm Dis. 2009 May;36(5):284-9. PMID: 19295472 -
Sutcliffe CG, German D, Sirirojn B, Latkin C, Aramrattana A, Sherman SG, Celentano DD. Patterns of methamphetamine use and symptoms of depression among youg adults in norther Thailand. Drug Alcohol Depend 2009. 101: 146-51. PMID: 19153017. -
Sherman SG, Sutcliffe CG, German D, Sirirojn B, Aramrattana A, Celentano DD. Patterns of Risky Behaviors Associated with Methamphetamine Use Among Young Thai Adults: A Latent Class Analysis. J Adolesc Health 2009; 44: 169-75. PMID: 19167666. -
Latkin C, Donnell D, Celentano DD, Aramrattana A, Liu T-Y, Vongchak T, Wiboonnatakul K, Metzger D. Relationships between social norms, social network characteristics, and HIV risk behaviors in Thailand and the U.S. Health Psych 2009; 323-9. PMID: 19450038. -
Kavasery R, Galai N, Astemborski J, Lucas GM, Celentano DD, Kirk GD, Mehta SH. Nonstructured treatment interruptions among injection drug users in Baltimore, MD. J Acquir Immune Defic Syndr 2009. 50:360-6. PMID: 19214124. -
Latkin W, Donnell D, Metzger D, Sherman S, Aramrattna A, Davis-Vogel A, Quan VM, Gandham S, Vongchak T, Perdue T, Celentano DD. The Efficacy of a Network Intervention to Reduce HIV risk Behaviors Among Drug Users and Risk Partners in Chiang Mai, Thailand and Philadelphia, USA. Soc Sci & Med 2009; 68: 740-8. PMID: 19070413 -
Solomon S, Subbaraman R, Solomon SS, Srikrishnan AK, Johnson SC, Vasudevan CK, Anand S, Ganesh AK, Celentano DD. Domestic Violence and Forced Sex Among the Urban Poor in South India: Implications for HIV Prevention. Violence Against Women 2009 May 15. PMID: 19448166. -
Genberg BL, Hlavka Z, Konda KA, Maman S, Chariyalertsak S, Chingono A, Mbwambo J, Modiba P, Van Rooyen H, Celentano DD. A comparison of HIV/AIDS-rtelated stigma in four countries: Negative attitudes and perceived acts of discrimination towards people lining with HIV/AIDS. Soc Sci Med 2009 May 6. PMID: 19427086. -
Towe VL, Sifakis F, Gindi RM, Sherman SG, Flynn C, Hauck H, Celentano DD. Prevalence of HIV Infection and Sexual Risk Behaviors Among Individuals Having Heterosexual Sex in Low Income Neighborhoods in Baltimore, MD: The BESURE Study. J Acquir Immune Defic Syndr. 2009 Oct 28. [Eprint] PMID: 19875965 -
Celentano D, Sherman S. The changing landscape of crack cocaine use and HIV infection. CMAJ 2009 Oct 27;181(9):571-2. Epub 2009 Oct 19. PMID: 19841049 -
Genberg BL*, Hlavka Z, Konda KA, Maman S, Chariyalertsak S, Chingono A, Mbwambo J, Modiba P, Van Rooyen H, Celentano DD. A comparison of HIV/AIDS-related stigma in four countires: negative attitudes and perceived acts of discrimination towards people living with HIV/AIDS. Soc Sci Med 2009;68:2279-87. PMID: 19427086. -
Panchanadeswaran S*, Johnson SC, Go VF, Srikrishnan AK, Sivaram S, Solomon S, Bentley M, Celentano DD. Using the theory of gender and power to examine experiences of partner violence, sexual negotiation, and risk of HIV/AIDS among economically disadvantaged women in Southern India. J Aggression, Maltreatment & Trauma (in press) -
Rugpao S, Rungruengthanakit K, Werawatanakul Y, Sinchai W, Ruengkris T, Lamlertkittikul S, Pinjareon S, Koonlertkit S, Limtrakul A, Sriplienchan S, Wongthanee A, Sirirojn B, Morrison CS, Celentano DD. Risk factors and algorithms for chlamydial and gonococcal cervical infections in women attending family planning clinics in Thailand. Sex Transm Infect (in press) -
Srithanaviboonchai K, Celentano DD, Visaruratana S, Kawichai S, Monjun V, Genberg B*, Chariyalertsak C, Simmons N, Chariyalertsak S. Perceptions about antiretroviral treatment, intentions to use condoms, and decisions to have an HIV test among rural northern lowland Thai and ethnic minority young adults. Asia Pacific J Public Health (in press) -
Hendriksen E, Celentano DD, Chariyalertsak S, chingono A, Gray GE, Khulich M, Mbwambo J, McIntyre J, Morin S, Richter L, Sweat T, Coates T. Communication, stigma, and VCT uptake in South Africa, Tanzania, Zimbabwe and Thailand. AIDS & Behav (in press). -
Solomon SS*, Desai M, Srikrishnan AK, Thamburaj E, Vasudevan CK, Kumar MS, Solomon S, Celentano DD, Mehta SH. The profile of injection drug users in Chennai, India: Identification of risk behaviors and implications for behavioral interventions. Substance Use Misuse (in press). -
Guadamuz TE, Kunawararak P, Beyrer C, Pumpaisanchai P, Wei C, Celentano DD. HIV prevalence, sexual and behavioral correlates among Shan, Hill tribe and Thai male sex workers in Northern Thailand. AIDS Care (in press). -
Yang X, Xia G, Li X, Latkin C, Celentano D. Social influence and individual risk factors of HIV unsafe sex among female entertainment workers in China. AIDS Educ Prev (in press). -
Sherman S, Sutcliffe CG, Srirojn B, German D, Thomson N, Aramrattana A, Celentano DD, Predictors and consequences of incarceration among a sample of young Thai methamphetamine users. Drug and Alcohol Review (in press). -
Nandi A, Celentano D. Neighborhood poverty and injection cessation in a sample of injection drug users. Am Journal of Epi (in press). -
Averbach SH, Gravitt PE, Nowak RG, Celentano DD, Dunbar MS, Morrison CS, Grimes B, Padian NS. The association between cervical HPV infection and HIV acquisition among women in Zimbabwe. AIDS. 2010 (accepted)
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