Professor
Associate Department Chair for Disease Prevention and Control
BA, Western Reserve University, 1967; MD, Harvard Medical School, 1971
Bloomberg School of Public Health
International Health
Disease Prevention and Control
Epidemiology, Medicine (School of Medicine)
- Donald S. Burke, M.D., is Professor of International Health and Epidemiology at the Johns Hopkins Bloomberg School of Public Health, where he serves as the Associate Chair and Director of the Disease Prevention and Control Program and Director of the Center for Immunization Research. His research interests include prevention, diagnosis, and control of infectious diseases of global importance. He is Principal Investigator of an international HIV Vaccine Trial; he leads a year-long seminar series on "Vaccine Science and Policy;" and he teaches a new course on "Infectious Disease Dynamics." Professor Burke's field research focuses on the epidemiology of emerging infectious diseases. He established and directs a project on cross-species transmission of infectious diseases in rain forest populations in Cameroon, Central Africa. He also leads a multi-institional "MIDAS" research group which which develops computational simulations and predictive models of infectious disease epidemiology and evolution, focusing on influenza, dengue, measles, and bioterrorist attacks.
- International health, vaccines, viruses, infectious diseases, epidemiology, HIV, AIDS, measles, dengue, smallpox, influenza, emerging infectious diseases, bioterrorism, computational models.
- PROFESSIONAL HONORS AND AWARDS
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Military Decorations and Awards (Colonel, Retired, US Army, after 23 years of active duty service)
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National Defense Service Medal, 1973; Army Service Ribbon, 1973; Army Commendation Medal, 1975; Meritorious Service Medal, 1978; Humanitarian Service Medal, 1981; Armed Forces Reserve Medal, 1984; Overseas Ribbon, 1984; Meritorious Service Medal, First Oak Leaf Cluster, 1985; Meritorious Service Medal, Second Oak Leaf Cluster, 1986; Order of Military Medical Merit, 1989; Department of the Army "A" Proficiency Designator, Infectious Diseases, 1990; National Defense Service Medal, First Oak Leaf Cluster, 1991; Meritorious Service Medal, Third Oak Leaf Cluster, 1991; Legion of Merit, 1997.
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Honors and Awards from Professional Organizations and Societies
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Phi Beta Kappa, 1966
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Omicron Delta Kappa, 1966
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Warrion Trophy, Western Reserve University, 1967
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Nathaniel A. Young Memorial Award, American Committee on Arthropod-borne Viruses, 1989.
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Kimble Methodology Award, Conference of Public Health Laboratorians, American Public Health Association,1989.
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Bailey K. Ashford Medal, American Society of Tropical Medicine and Hygiene, 1990.
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Sustaining Membership Lectureship, Association of Military Surgeons of the US, 1992.
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Elected President, American Society of Tropical Medicine & Hygiene, 1995.
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Golden Apple Award, Johns Hopkins School of Hygiene and Public Health, 1999.
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Delta Omega, Public Health Honorary Society, 2000.
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Elected Fellow, American Academy of Microbiology, 2000
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Thomas Francis Jr. Memorial Lectureship and Medal, 2001
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Elected Fellow, American Association for the Advancement of Science (Medical Science), 2003
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Centennial Anniversary Lecturer, American Society of Tropical Medicine and Hygiene, 2003.
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Lecturer, Annual Meeting of the National Academy of Sciences, 2004
Research Projects
Vaccine Modeling Initiative
Evaluation of candidate vaccine technologies using computational models.
- Cummings DAT, Schwartz IB, Billings L, Shaw LB, Burke DS. Dynamic effects of antibody dependent enhancement on the fitness of viruses. Proc Natl Acad Sci USA 102:15259-64 (2005).
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Ferguson NM, Cummings DAT, Cauchemez S, Fraser C, Riley S, Meeyai A, Iamsirithworn S, Burke DS. Evaluation of the likely effectiveness of strategies for containing an emerging influenza pandemic in Southeast Asia. Nature 437:209-14 (2005).
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Wolfe ND, Heneine W, Carr JK, Garcia AD, Shanmugam V, Tamoufe U, Torimiro JN, Prosser AT, Lebreton M, Mpoudi-Ngole E, McCutchan FE, Birx DL, Folks TM, Burke DS, Switzer WM. Emergence of unique primate T-lymphotropic viruses among central African bushmeat hunters. Proc Natl Acad Sci U S A 102: 7994-9 (2005).
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Gilbert PB, Peterson ML, Follmann D, Francis DP, Gurwith M, Heyward WL, Hudgens MG, Jobes DV, Popovic V, Self SG, Sinangil F, Burke DS, Berman PW. Immunologic responses to rgp120 vaccine correlate with the incidence of HIV-1 infection in a phase 3 preventive HIV-1 vaccine trial. J Infect Dis 191: 666-77 (2005)
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Burke DS. Lessons learned from the 1954 Field Trial of Poliomyelitis Vaccine. Clinical Trials 1: 3-5. (2004).
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Waters HR, Dougherty L, Tegang S-P, Tran N, Wiysonge CS, Long K, Wolfe ND, Burke DS. Coverage and Costs of childhood immunizations in Cameroon. Bulletin of the World Health Organization. 82(9), 668-675 (2004).
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Oh S, Perera LP, Burke DS, Waldmann TA, Berzofsky JA. IL-15/IL-15R alpha-mediated avidity maturation of memory CD8+ T cells. Proc Natl Acad Sci U S A. 101(42):15154-15159 (2004)
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Kijak GH, Sanders-Buell E, Wolfe ND, Mpoudi-Ngole E, Kim B, Brown B, Robb ML, Birx DL, Burke DS, Carr JK, McCutchan FE. Development and application of a high-throughput HIV type 1 genotyping assay to identify CRF02_AG in West/West Central Africa. Aids Research and Human Retroviruses. 20(5), 521-30 (2004).
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Wolfe ND, Switzer WM, Carr JK, Bhullar VB, Shanmugam V, Tamoufe U, Prosser AT, Torimiro JN, Wright A, Mpoudi-Ngole E, McCutchan FE, Birx DL, Folks TM, Burke DS, Heneine W. Naturally acquired simian retrovirus infections in central African hunters. Lancet. 363(9413), 932-7 (2004).
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Cummings DA, Irizarry RA, Huang NE, Endy TP, Nisalak A, Ungchusak K, Burke DS. Travelling waves in the occurrence of dengue haemorrhagic fever in Thailand. Nature. 427(6972), 344-7 (2004).
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Oh S, Berzofsky JA, Burke DS, Waldmann TA, Perera LP. Coadministration of HIV vaccine vectors with vaccinia viruses expressing IL-15 but not IL-2 induces long-lasting cellular immunity. Proceedings of the National Academy of Sciences (USA). 100(6), 3392-7 (2003).
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Oh S, Hodge JW, Ahlers JD, Burke DS, Schlom J, Berzofsky JA. Selective induction of high avidity CTL by altering the balance of signals from APC. Journal of Immunology. 170(5), 2523-30 (2003).
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Nisalak A, Endy TP, Nimmannitya S, Kalayanarooj S, Thisayakorn U, Scott RM, Burke DS, Hoke CH, Innis BL, Vaughn DW. Serotype-specific dengue virus circulation and dengue disease in Bangkok, Thailand from 1973 to 1999. The American Journal of Tropical Medicine and Hygiene. 68(2), 191-202 (2003).
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