Professor
Editor-in-Chief, Environmental Research
PhD '72, Johns Hopkins, Environmental Engineering SciencesAB '67, Vassar College, Modern History
Bloomberg School of Public Health
Environmental Health Sciences
Environmental Health Engineering
Health Policy and Management; Epidemiology
Johns Hopkins Center in Urban Environmental Health
- Trained at Hopkins in geography and environmental engineering (PhD '72) and postdoctoral fellow in Environmental Health Sciences ('72-75). NIH staff fellowship followed by senior scientist position at Environmental Defense and professorship at University of Maryland Medical School. Served as scientific advisor to NTP-NIH, CDC, EPA, DOE, OSHA, states of Maryland and New York, World Bank, ILO, UNEP, and PAHO.
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My research and professional activities bridge science and public policy, with a focus on the incorporation of mechanistic toxicology into environmental and occupational health policy. Areas of current focus include: cardiovascular risks of arsenic, lead, and cadmium; immunotoxicity of mercury compounds; health and environmental impacts of industrial food animal production. These projects include epidemiological studies and mechanistic research on gene:environment interactions and movement of pathogens in the environment. Some of this research is conducted internationally (mercury studies in the Amazon; lead/cadmium/arsenic studies in Mexico; mining and development in Mongolia; zoonotic diseases in Thailand and the Netherlands).
- Environmental Health Sciences, antibiotic-resistant bacteria, lead, mercury, immunotoxicology, neurotoxicology, environment
- Fellowships from Fulbright, Kennedy, Rockefeller, Danforth, Woodrow Wilson Foundations. Phi Beta Kappa, Vassar College. Barsky Award, Amer Public Health Assn. MacArthur Foundation "Genius" Fellow. Editor in Chief: Environmental Research. Member, scientific advisory councils for EPA, PAHO, CDC, Department of Energy, NIH-NIEHS. Consultant, World Bank, WHO, UNEP, OSHA, and ILO.
Research Projects
Exposures to mercury in small scale goldmining
we are examining exposures to mercury among gold miners and fish consumers in Amazonian Brazil; outcomes include health status with an emphasis on interactions with malaria and other infectious diseases and assessment of molecular biomarkers for autoimmunity
- One reservoir: redefining the community origins of antimicrobial resistant infections. Med Clin NA (2008) 92: 1391-1407
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Industrial food animal production, antimicrobial resistance, and human health. Silbergeld EK, Graham J, and Price LB. Ann Rev Pub Health 29: 151-169, 2008.
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The animal-human interface and infectious disease in industrial food animal production. Graham JP, Leibler JH, Price LB, Otte MG, Pfieffer DU, Tiensin T, Silbergeld, EK. Pub Health rep 123: 282-299, 2008.
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A probabilistic risk assessment of Cryptosporidium exposure among Baltimore urban anglers. Roberts JD, Silbergeld, EK, and Graczyk T. J Toxicol Environ Health, Part A, 70: 11368-1376, 2007.
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Mercury exposure and murine response to Plasmodium yoelii infection and immunization. Silbergeld EK, Sacci JB Jr, Azad AF. Immunotoxicol Immunopharmacol 22: 685-695, 2000.
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Lead as a carcinogen: experimental evidence and mechanisms of action. Silbergeld EK, Waalkes M, and Rice JM. Amer J Indust Med 38: 316-323, 2000.
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Methylmercury induced decrement in neuronal migration may involve cytokine-dependent mechanisms. Sass JB, Haselow DT, and Silbergeld EK. Toxicol Sci 63: 74-81, 2001.
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Animal antibiotic use has an early but important impact on the emergence of antibiotic resistance in human commensal bacteria. Smith DL, Harris AD, Johnson JA, Silbergeld EK, and Morris JG. PNAS 99:(9); 6434-6439, 2002.
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Assessment of mercury exposure and malaria in a Brazilian Amazon riverine community. Crompton P, Ventura AM, de Souza JM, Santos E, GT, and Silbergeld EK. Environ Res 90: 69-75, 2002.
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Blood lead levels and mortality. Lustberg M and Silbergeld EK. Arch Intern Med 162: 2443-2449, 2002.
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Low-dose exposure to inorganic mercury accelerates disease and mortality in acquired murine lupus. Via, CS, Nguyen, P, Niculescu, F, Papadimitriou, J, Hoover, D, Silbergeld, EK. Environ Health Perspect 111: 1273-7, 2003.
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Mercury exposure, malaria, and serum antinuclear/antinucleolar antibodies in amazon populations in Brazil: a cross-sectional study. Silva IA, Nyland JF, Gorman A, Perisse A, Ventura AM, Santos ECO, de Souza JM, Burek CL, Rose NR, Silbergeld EK. Environ Health 3:(1)11, 2004.
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Prenatal HgCl2 exposure in BALB/c mice: gender-specific effects on the ontogeny of the immune system. Silva IA, El Nabawi M, Hoover D, Silbergeld EK. Dev Comp Immunol 29: 171-183, 2005.
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Neurologic symptoms and neuropathologic antibodies in poultry workers exposed to Campylobacter jejeuni. J Occup Environ Med 49: 748-755, 2007.
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