Assistant Professor
Deputy Director, Center for Clinical Global Health Education
B.Sc. MIT 1991, M.D. Harvard Medical School 1997, MHS Bloomberg School of Public Health (anticpted 2006)
School of Medicine
Medicine
Infectious Diseases
Center for Clinical Global Health Education
- Dr. Amita Gupta, Deputy Director of the Johns Hopkins University (JHU) Center for Clinical Global Health Education (CCGHE), is an Assistant Professor of Infectious Diseases at JHU. Born to Indian parents, she grew up in the United States, England and France. She completed her undergrad education at Massachusetts Institute of Technology, medical degree at Harvard Medical School, and primary care and internal medicine training at San Francisco General Hospital-University of California San Francisco. She was an Epidemic Intelligence Service Officer focusing on global foodborne and diarrheal diseases epidemiology at the US Centers for Disease Control and Prevention (CDC) before completing an infectious diseases fellowship at JHU.
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During her years of training, Dr. Gupta worked internationally including Guatemala, Vietnam, Micronesia and India. Dr. Gupta is an infectious diseases and HIV clinician at Johns Hopkins School of Medicine. She is also an active clinical investigator in multi-country HIV trials conducted by the AIDS Clinical Trials Group (ACTG), HIV Prevention Trials Network (HPTN) and Internatonal Maternal Pediatric Adolescent AIDS Trials Network (IMPAACT) focusing on prevention and care of HIV, TB and other co-mordities and treatment outcomes in adults, including pregnant women, and children residing in low-income settings.
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Dr. Gupta works with colleagues at the National AIDS Research Institute (NARI) and the BJ Medical College in Pune, India, as well as with private practitioners. Dr. Gupta is now also working with others in India to understand the use of traditional Indian medicines such as Ayurveda among HIV-infected persons.
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As Deputy Director of the JHU CCGHE, Dr. Gupta is working with a terrific team to develop online clinical care training courses that are geared for care in resource-limited regions of the world. Dr. Gupta enjoys teaching clinical medicine and enjoys collaborating on educational initiatives to enhance practical clinical knowledge globally.
- HIV in India, MTCT, care and treatment, drug resistance, HIV/TB in pregnant women, nutritional status and HIV outcomes, HIV clinical trials in resource-constrained settings
- Mackel Finalist, EIS Conference 2002
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U.S. Public Health Service Award for Foreign Duty Service (cholera in Micronesia), 2002
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U.S. Public Health Service Award for Bioterrorism surveillance post 9/11, 2002
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IDSA Special Citation for Fellows-in-Training, 2001
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Reza Gandeji Award (UCSF resident award for medical ethics and compassionate patient care), 2000
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Paul Dudley White & Andrew Sellard Traveling Fellowship, 1996
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Harvard Medical School Urban Health Fellowship, 1993
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Sigma Xi Research Honor Society, 1991
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MIT Student Humanitarian Award, 1991
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MIT Women Studies Writing Prize “Women and AIDS in the United States: Unheard Voices,” 1991
Research Projects
A5207 A Phase II randomized comparison of three antiretroviral strategies administered for 7 or 21 days to reduce the emergence of nevirapine resistant HIV-1 following a single intrapartum dose of nevirapine
Phase II, prospective, randomized, open-label study evaluating the effectiveness of three different antiretroviral strategies administered for 7 or 21 days for the prevention of nevirapine resistance after a single intrapartum dose of nevirapine (SD NVP). All antiretroviral agents will be...
A5263 Three Chemo Regimens as an Adjunct to ARV Therapy for Treatment of AIDS-KS
ART and chemotherapy for Kaposi''s Sarcoma
A5274 ACTG REMEMBER
Public health approach of empiric TB treatment vs. standard approach to reduce early mortality in advanced HIV
Diagnosis of active tuberculosis in HIV infected and uninfected young children in India
Tuberculosis (TB) is the most common cause of morbidity/mortality in HIV-infected individuals in India, which has among the world''''''''''''''''s highest burden of HIV and TB. Since children acquire HIV/TB from their caregivers, active TB is highly prevalent (14-67.5%) among HIV-infected young...
Examination of the Role of Traditional Medicine for HIV/AIDS in India
This is a pilot study, funded by the Samueli Institute for Information Biology, designed to examine the role of traditional Indian medicines and homeopathy for the management of HIV/AIDS and associated illnesses in India. No cost extension pending.
HPTN 052: A Randomized Trial to Evaluate the Effectiveness of Antiretroviral Therapy Plus HIV Primary Care versus HIV Primary Care Alone to Prevent the Sexual Transmission of HIV-1 in Serodiscordant Couples
HPTN 052 is a Phase III, two-arm, multi-site, randomized trial to determine the effectiveness of two treatment strategies in preventing the sexual transmission of HIV in HIV-serodiscordant couples. As part of the National AIDS Research Institute's CTU, the primary objective of this study is to...
Impact of Malnutrition on HIV Treatment Failure in Resource-Limited Settings
Highly active antiretroviral therapy (HAART) has reduced morbidity and mortality in HIV-infected persons worldwide. However, early treatment failure (i.e. WHO stage 3 or 4 illnesses or death during the first 12 months of HAART) is >3-fold higher in resource limited settings (RLS) than in resource...
P1060 Phase II, parallel, randomized, clinical trials comparing the responses to initiation of NNRTI-based vs. PI-based antiretroviral therapy in HIV-infected infants who have and have not previously received single dose nevirapine for prevention of mother-to-child transmission
A Phase II, randomized, controlled trial of HIV-infected infants and children between 6 months and 36 months of age who are eligible for ART as defined by the current WHO pediatric algorithm. Infants/children will be enrolled in one of two cohorts based on NVP exposure. Within each cohort, they...
- Moorthy A, Gupta A, Bhosale R, Tripathy S, Sastry J, Kulkarni S, Thakar M, Bharadwaj R, Kagal A, Bhore AV, Patil S, Kulkarni V, Varadharajan V, Balasubramaniam U, Suryavanshi N, Ziemniak C, Gupte N, Bollinger R, Persaud D. Nevirapine resistance and breast-milk HIV transmission: effects of single and extended-dose nevirapine prophylaxis in subtype C HIV-infected infants. PLoS One 2009:4(1):e4096.
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Passaretti C, Gupta A. Correspondence to Hurwitz et al Suppression of human immunodeficiency virus type 1 viral load with selenium supplementation. Arch Int Med 2007 Dec 10/24; 167(22) 2530-31.1)
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Gupta A, Anand S, Sastry J, Krisagar A, Basavaraj A, Bhat, SM, Gupte N, Bollinger RC, Kakrani AL. High risk for occupational exposure to HIV and utilization of post-exposure prophylaxis in a teaching hospital in Pune, India. BMC Infectious Diseases 2008 Oct 21:8:142.
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Fritts M, Crawford CC, Quibell D, Gupta A, Jonas WB, Coulter ID, Andrade A. Traditional Indian Medicine and Homeopathy for HIV/AIDS: A Review of the Literature. AIDS Res Therapy.
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Singh HK, Gupta A, Siberry GK, Gupte N, Sastry J, Kinikar A, Shah I, Gangakhedkar RR, Bollinger RC, Kulkarni V. The Indian pediatric HIV epidemic: a systematic review. Curr HIV Res 2008; 6:419-432.
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Six Week Extended-Dose Nevirapine (SWEN) Study Team. Extended-dose nevirapine to 6 weeks of age for infants to prevent HIV transmission via breastfeeding in Ethiopia, India, and Uganda: an analysis of three randomized controlled trials. Lancet 2008; 372(9635):300-313.
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Gupta A, Gupte N, Bhosale R, Kakrani A, Kulkarni V, Nayak U, Thakar M, Sastry J, Bollinger RC; for the Byramji Jeejeebhoy Medical College-Johns Hopkins University Study Group. Low sensitivity of total lymphocyte count as a surrogate marker to identify antepartum and postpartum Indian women who require antiretroviral therapy. J Acquir Immune Defic Syndr 2007; 46(3): 338-42.
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Gupta A, Sastry J, Suryawanshi N, Pisal H, Kulkarni P, Bharucha KE, Bulakh P, Gupte N, Krisagar A, Tripathy S, Paranjape R, Bhore AV, Ambike N, Choi J, Nayak J, Phadke M, Bollinger RC. Mother-to-child transmission of HIV among women who chose not to exlusively breastfeed their infants in Pune, India. Ind J Med Res 2007; 126: 89-93
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Sobhani RM, Basavaraj A, Gupta A, Bhave AS, Kadam DB, Sangle SA, Prasad HB, Choi J, Josephs J, Gebo KA, Morde SN, Bollinger RC, Kakrani AL. Inpatient mortality, clinical characteristics and length of stay among HIV-infected persons attending a public hospital in Pune, India. Indian J Med Res 2007; 126:112-7.
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Gupta A., Nayak U., Ram M., Bhosale R., Patil S., Basavraj A., Kakrani A., Phillip S., Desai D, Sastry J., Bollinger R., MIT-BJMC-JHU Study Group. Post-partum TB incidence and mortality among HIV-infected women and their infants in Pune, India 2002-2005. Clin Infect Dis 2007; 45:241-9.
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Sinha G, Choi J, Nayak U, Gupta A, Nair S, Gupte N, Bulakh PM, Sastry J, Deshmukh SD, Khandekar MM, Bhore AV, Melinkeri RR, Kulkarni VP, Bhosale RA, Naphade PR, Bharucha KE, Phadke MA, Kshirsagar AS, Bollinger RC. Clinically-significant anemia in HIV-infected pregnant women in India is not a major barrier to zidovudine use for prevention of maternal-to-child transmission. J Acquir Immune Defic Syndr 2007; 45:210-17
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Shah B, Walshe L, Saple DG, Ramini R, Kharkar S, Bollinger RC, Gupta A. Antiretroviral adherence and virologic suppression among HIV-infected patients attending private clinics in Mumbai. Clin Infect Dis 2007; 44(9)1235-44.
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Polis C, Shah S, Johnson K, Gupta A. Impact of maternal HIV co-infection on the vertical transmission of Hepatitis C virus: a meta-analysis. Clin Infect Dis 2007; 44(8) 1123-1131.
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Ramachandani S, Saple DJ, Mehta S, Bollinger RC, Gupta A. Knowledge, Attitudes, and Practices among HIV-infected persons in India regarding antiretroviral therapy. Accepted. AIDS Patient Care and STDs.
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Mehendale SM, Kishore Kumar B, Ghate MV, Sahay S, Gamble T, Godbole SV, Gupta A, Gangakhedkar RR, Divekar AD, Risbud AR, Paranjape RS, Bollinger RC Low Risk of HIV-1 Transmission among married couples in India. JAIDS. 2006 Mar;41(3):371-3.
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Book chapters
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1)Gupta A, Hirschhorn LR, Piliero PJ and Gallant JE. Diagnostic Approach to Common Clinical Syndromes. In: HIV. 3rd edition. Libman H and Makadon H, Editors. American College of Physicians. Philadelphia, 2007.
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2)Contributing author to Johns Hopkins University HIV Poc-It Guide, 2009. Salmonella and HIV. Post-exposure prophylaxis. Blastomycosis. Cryptococcal meningitis.Cocciodioimycosis.Histoplasmosis. Esophageal Candidiasis. Oral Candiadiasis.
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3) Conn's Current Therapy. The patient with HIV Disease. 2010 (in press)
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4)Gupta A, Bollinger RC. Combating HIV/AIDS: The need for public-private health partnerships, In: Global Scenario on HIV and AIDS: Is There a Way Out? Eds: Naveen Kumar and VV Ramani, Icfai University Press, Hyderabad, India 2008.
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