Taha E. Taha

Professor
Co-Director, Infectious Disease Epidemiology

Academic Degrees

PhD, The Johns Hopkins University 1992; MPH, San Diego State University 1986; MCM, University of Khartoum 1982; MBBS, University of Khartoum 1975

School/Organization
Bloomberg School of Public Health

Department / Division
Epidemiology
Infectious Disease Program

Joint Departmental Affiliations
Population and Family Health Sciences

Center and Institute Affiliations
Center for Global Health

Departmental Address
Room E7138
615 North Wolfe Street; Baltimore, Maryland 21205

Email: ttaha@jhsph.edu
Phone: +1.410.614.5255
Fax: +1.443.287.5188

For more information visit my personal web page.

Research and Professional Experience

• To continue epidemiologic research in the fields of HIV/AIDS, sexually transmitted diseases (STDs), and tropical diseases. In particular, to design, conduct, and evaluate non-vaccine (including use of antiretrovirals and microbicides)and vaccine interventions to reduce heterosexual and mother-to-child transmission of HIV. The mortality and morbidity impact of infectious diseases such as HIV, malaria, and STDs on mothers and children is of special interest. Development and testing of low cost intereventions is a major research direction. Training of scientists in conventional and non-conventional fields of Public Health is a commitment.

Honors and Awards

• SOCIETY MEMBERSHIP:
• Member-American Epidemiological Society
• Member-American College of Epidemiology
• Member-International Society of Epidemiology
• Member-American Society of Tropical Medicine and Hygiene
• AWARDS:
• 2004-The Gustav J. Martin Innovation Research Fund Award, The Johns Hopkins Bloomberg School of Public Health.
• 1992-The Paul A. Harper Award, The Johns Hopkins University.
• 1991-92-The Population Council Fellowship.
• 1988-90-The African Dissertation Fellowship Award, The Rockefeller Foundation.
• 1986-88-Jessie Smith Noyes Foundation Fellowship.
• 1986-Outstanding Graduate Award, San Diego State University.
• 1986-John Hanlon Award, Graduate School of Public Health, San Diego State University.
• 1984-86-The African American Institute Fellowship.

Research Projects
AIDS International Training and Research Program (Fogarty AITRP)
Chris Beyrer, MD, MPH, Principal Investigator Taha E. Taha, MD, PhD, Country Director for Malawi The JHU Fogarty International Training and Research Program (JHU-AITRP) provides greatly needed opportunities for the training of Malawians in the fields of HIV, STDs, epidemiology, vaccinology,...

Center for HIV/ AIDS Vaccine Immunology (CHAVI)
CHAVI 001 studies the HIV-1 virus specifically to determine the prevalence of acute HIV infection, characteristics of the transmitted virus in acute HIV-1 infection, host acquired and innate immune responses that contribute to virus control and/or protection against infection with HIV-1, genetic...

Interventional Epidemiologic Research Studes to Reduce Mother-to-Child HIV-1 Transmission and Improve Infant Survival in Resource-Limited Countries of High HIV-1 Seroprevalence
The PEPI-Malawi study is a randomized, open-label, controlled phase III trial of extended post-exposure prophylactic antiretrovirals to prevent breastmilk-associated HIV transmission. The study population consists of women and their babies attending antenatal clinics and/ or admitted to labor...

The Malawi Clinical Trials Unit
The Malawi Clinical Trials Unit (CTU) - in collaboration with the College of Medicine-University of Malawi and the University of North Carolina - Chapel Hill - conducts prevention, microbicide, perinatal and antiretroviral trials as well as develops educational and scientific infrastructure in...



Selected Publications

• INTERVIEWS:
• Med Page Today: http://www.medpagetoday.com/HIVAIDS/HIVAIDS/9701
• PUBLICATIONS:
• Kumwenda NI, Hoover DR, Mofenson LM, Thigpen MC, Kafulafula G, Li Q, Mipando L, Nkanaunena K, Mebrahtu T, Butlerys M, Fowler MG, Taha TE. Extended Antiretroviral Prophylaxis to Reduce Breast-Milk HIV-1 Transmission. New England Journal of Medicine, 2008: 359(2):119-129.
• Kumwenda NI, Kumwenda J, Kafulafula G, Makanani B, Taulo F, Nkhoma C, Qi L, Taha TE. HIV-1 Incidence among Women of Reproductive Age in Malawi. International Journal of STD & AIDS, 2008; 19 (5): 339-341.
• Kumwenda JJ, Makanani B, Taulo F, Nkhoma C, Kafulafula G, Li Q, Kumwenda N, Taha TE. Natural History and Risk Factors Associated with Early and Established HIV-1 Infection among Reproductive Age Women in Malawi. Clinical Infectious Diseases. 2008: 46(12): 1913-1920.
• Gulia J, Kumwenda N, Li Q, Taha TE. HIV Seroreversion Time in HIV-1. Uninfected Children Born to HIV-1 Infected Mothers in Malawi. Journal of Acquired Immune Deficiency Syndrome, 2007; 46(3): 332-337.
• Taha TE, Hoover DR, Kumwenda NI, Fiscus SA, Kafulafula G, Nkhoma C, Chen S, Piwower E, Broadhead RL, Brooks Jackson J, Miotti PG. Late Postnantal Transmission of HIV-1 and Associated Factors. Journal of Infectious Diseases. 2007;196(1):10-4.
• Goldenberg RL, Andrews WW, Hoffman I, Fawzi W, Valentine M, Young A, Read JS, Brown ER, Mudenda V, Kafulafula G, Mwinga K, Taha TE. Fetal fibronectin and adverse infant outcomes in a predominantly human immunodeficiency virus-infected African population: a randomized controlled trial. Obstetrics and Gynecology 2007; 109: 392-401.
• Eshleman SH, Lie Y, Hoover Dr, Chen S, Hudelson SE, Fiscus SA, Petropoulos CJ, Kumwenda N, Parkin N, Taha TE. Association of HIV-1 replication capacity (RC) with HIV-1 mother-to-child transmission among antiretroviral drug naïve Malawian women. Journal of Infectious Diseases. 2006; 193 (11):1512-1515.
• Taha TE, Kumwenda N, Kafulafula G, Makanani B, Nkhoma C, Chen S, Tsui A, Hoover DR. Intermittent Intravaginal Antibiotic Treatment of Bacterial Vaginosis in HIV-Uninfected and Infected Women: A Randomized Clinical Trial. PLoS Clin Trials 2(2): e10.
• Kumwenda N, Hoffman I, Chirenje M, Kelly C, Coletti A, Ristow A, Martinson F, Brown J, Chilongozi D, Richardson B, Rosenberg Z, Padian N, Taha T. HIV incidence among women of reproductive age in Malawi and Zimbabwe (HIVNET/ HPTN 016). Sexually Transmitted Diseases 2006; 33(11): 646-651.
• Taha TE, Kumwenda NI, Hoover DR, Kafulafula G, Fiscus SA, Nkhoma C, Chen S, Broadhead RL. The impact of breastfeeding on the health of HIV-1 infected mothers and their children in sub-Saharan Africa. Bulletin of the World Health Organization 2006; 84(7): 546-554.
• Taha TE, Brown ER, Hoffman I, Fawzi W, Read JS, Sinkala M, Martinson F, Kafulafula G, Masamanga G, Valentine M, Emel L, Mwatha A, Adeniyi-Jones S, Goldenberg R. A phase III clinical trial of antibiotics to reduce chorioamniontis-related perinatal HIV-1 transmission. AIDS 2006; 20: 1313 – 321.
• Biggar RJ, Taha TE, Hoover D, Kumwenda N, Broadhead R. Higher HIV infection risk in girls than boys infected in utero or perinatally. Journal of Acquired Immune Deficiency Syndromes 2006; 41: 509-513.
• Goldenberg RL, Mudenda V, Read JS, Brown ER, Sinkala M, Kamiza S, Martinson F, Kaaya E, Hoffman I, Fawzi W, Valentine M, Taha TE and the HPTN 024 Study Team. HPTN 024 study: Histologic chorioamnionitis, antibiotics and adverse infant outcomes in a predominantly HIV-1-infected African population. American Journal of Obstetrics and Gynecology 2006; 195(4): 1065-1074.
• Goldenberg RL, Mwatha A, Read JS, Adeniyi-Jones S, Sinkala M, Masamanga G, Martinson F, Hoffman I, Fawzi W, Valentine M, Emel L, Brown E, Mudenda V, Taha TE and the HPTN 024 Team. The HPTN 024 study: the efficacy of antibiotics to prevent chorioamnionitis and preterm birth. American Journal of Obstetrics and Gynecology 2006; 194(3): 650-661.
• Eshleman SH, Hoover DR, Hudelson SE, Chen S, Fiscus SA, Piwowar-Manning E, Jackson JB, Kumwenda NI, Taha TE. Development of nevirapine resistance is reduced by using infant-only nevirapine plus zidovudine post-exposure prophylaxis to prevent HIV-1 mother-to-child transmission. Journal of Infectious Diseases 2006; 193(4): 479-481.
• Eshleman SH, Church JD, Hoover DR, Chen S, Guay LA, Mwatha A, Fiscus SA, Mmiro F, Musoke P, Jackson JB, Kumwenda N, Taha T. Comparison of risk of HIV-1 mother-to-child transmission among Malawian women with subtype C and Ugandan women with subtypes A and D after single dose nevirapine prophylaxis. Journal of Infectious Diseases, 2005;192: 30–36.
• Eshleman SH, Hoover DR, Chen S, Hudelson SE, Guay LA, Mwatha A, Fiscus SA, Mmiro F, Musoke P, Jackson JB, Kumwenda N, Taha T. Resistance after single dose nevirapine prophylaxis emerges in a high portion of Malawian newborns. AIDS 2005; 19(18): 2167-2169.
• Taha TE, Kumwenda N, Mwakomba A, Mwenda R, Kawonga H, Nyasulo P, Soko D, Chen S, Hoover D, Kafulafula G. Safety, acceptability and potential efficacy of a topical penile microbicide wipe. Journal of Acquired Immune Deficiency Syndromes 2005; 39:347-353.
• Taha TE, Nour S, Kumwenda NI, Broadhead RL, Fiscus SA, Kafulafula G, Nkhoma C, Chen S, Hoover DR. Gender differences in perinatal HIV acquisition among African infants. Pediatrics 2005, 115: 167 – 172.
• Taha TE, Kumwenda N, Kafulafula G, Kumwenda J, Chitale R, Nkhoma C, Katundu P, Mukiibi J, Miotti P, Hoover D, Broadhead R. Hematological changes among children who received short-term prophylaxis with nevirapine and zidovudine at birth. Annals of Tropical Paediatrics 2004, 24: 301- 309.
• Taha TE, Kumwenda NI, Hoover DR, Fiscus SA, Kafulafula G, Nkhoma C, Nour S, Chen S, Liomba G, Miotti PG, Broadhead RL. Nevirapine and zidovudine at birth to reduce transmission of HIV from mother to infant in an African setting: randomized clinical trial. Journal of the American Medical Association 2004, 292: 202 – 209.
• Taha TE, Kumwenda NI, Gibbons A, Broadhead RL, Fiscus S, Lema V, Liomba G, Nkhoma C, Miotti PG, Hoover DR. Short postexposure prophylaxis in newborn babies to reduce mother-to-child transmission of HIV-1: NVAZ randomized clinical trial. Lancet 2003, 362: 1171-1177.
• Kumwenda N, Taha TE, Celentano DD. Response to “Unexplained high HIV-1 incidence in a cohort of Malawi men”: Letter to the Editor. Sexually Transmitted Diseases 2003; 30(2):185.
• Sutcliffe S, Taha TE, Kumwenda N, Taylor E, Liomba GN. HIV-1 prevalence and herpes simplex virus 2, hepatitis C virus and hepatitis B virus infections among male workers at a Sugar Estate in Malawi. Journal of Acquired Immune Deficiency Syndromes 2002, 3:90-97.
• Kumwenda NI, Taha TE, Hoover D, Markakis D, Liomba NG, Chiphangwi JD, Celentano DD. Three surveys of HIV-1prevalence and risk factors among men working at a Sugar Estate in Malawi. Sexually Transmitted Diseases 2002, 29:366-371.
• Taha TE, Kumwenda N, Gibbons A, Hoover D, Lema V, Fiscus S, Mukiibi J, Liomba G, Broadhead R. Effect of HIV-1 antiretroviral prophylaxis on hepatic and hematological parameters of African infants. AIDS 2002, 16:851-858.
• Semba RD, Taha TE, Kumwenda N, Mtimavalye L, Broadhead R, Miotti PG, Chiphangwi JD. Iron status and indicators of human immunodeficiency deficiency disease severity among pregnant women in Malawi. Clinical Infectious Diseases 2001, 32:1496-1499
• Taha TE, Gray RH. Genital tract infections and perinatal transmission of HIV. Annals New York Academy of Sciences 2000, 918:84-98.
• Taha, T.E., Graham, S.M., Kumwenda, N.I., Broadhead, R.L., Hoover, D.R., Markakis, D., Hoeven, L.V.,D., Liomba, G.N., Chiphangwi, J.D., Miotti, P.G. Morbidity among HIV-1 infected and uninfected African children. Pediatrics 2000, 106(6):e77.
• Taha, T. E., Gray, R. H. Genital tract infections and perinatal transmission of HIV. Annals New York Academy of Sciences 2000, 918:84-98.
• Taha, T.E., Kumwenda, N.I., Hoover, D.R., Biggar, R.J., Broadhead, R.L., Cassol, S., Hoeven, L.V.,D., Markakis, D., Liomba, G.N., Chiphangwi, J.D., Miotti, P.G. Association of HIV-1 load and CD4+ lymphocyte with mortality in untreated African children older than one year. AIDS 2000, 14:453-459.
• Taha, T.E., Graham, S.M., Kumwenda, N.I., Broadhead, R.L., Hoover, D.R., Markakis, D., Hoeven, L.V.,D., Liomba, G.N., Chiphangwi, J.D., Miotti, P.G. Morbidity among HIV-1 infected and uninfected African children. Pediatrics 2000, 106:URL: http://www.pediatrics.org/cgi/content/full/106/6/e77.
• Taha, T.E., Kumwenda, N.I., Hoover, D.R., Biggar, R.J., Broadhead, R.L., Cassol, S., Hoeven, L.V.,D., Markakis, D., Liomba, G.N., Chiphangwi, J.D., Miotti, P.G. Association of HIV-1 load and CD4+ lymphocyte with mortality in untreated African children older than one year. AIDS 2000, 14:453-459.
• Ioaninidis JPA, Taha TE, Kumwenda N, Broadhead R, Mtimavalye L, Miotti P, Yellin F, Contoploulos-Ioannidis DG, Biggar RJ. Predictors and impact of losses to follow-up in a HIV-1 perinatal transmission cohort in Malawi. International Journal of Epidemiology. 1999, 28:769-775.
• Miotti, P.G., Taha, T.E., Kumwenda, N.I., Broadhead, R., Mtimavalye, L.A.R., Hoeven, L.V.D., Chiphangwi, J.D., Liomba, G., Biggar, R.J. HIV transmission from breastfeeding: a study from Malawi. JAMA 1999, 282:744-749.
• Taha, T.E., Kumwenda, N.I., Broadhead, R.L., Hoover, D.R., Graham, S.M., Hoeven, L.V.,D., Markakis, D., Liomba, G.N., Chiphangwi, J.D., Miotti, P.G. Mortality after the first year of life among HIV infected and uninfected children. Pediatric Infectious Diseases Journal 1999, 18:689-694.
• Taha, T.E., Gray, R.H., Kumwenda N.I, Hoover, D.R., Mtimavalye, L.A.R., Liomba, G.N., Chiphangwi, J.D., Dallabetta, G.A., Miotti, P.G. HIV infection and disturbances of vaginal flora during pregnancy. Journal Acquired Immune Deficiency Syndromes and Human Retrovirology 1999, 20: 52-59.
• Taha, T.E., Hoover, D.R., Dallabetta, G.A., Kumwenda, N.I., Mtimavalye, L.A.R., Ping, Yang, L-p., Liomba G.N., Broadhead, R.L., Chiphangwi, J.D., Miotti, P.G. Bacterial vaginosis and disturbances of vaginal flora: association with increased acquisition of HIV. AIDS 1998, 12: 1699-1706.
• Taha, T.E., Dallabetta, G.A., Hoover, D.R., Chiphangwi, J.D., Mtimavalye, L.A.R., Liomba, G., Kumwenda, N.I., Miotti, P.G. Trends of HIV-1 and sexually transmitted diseases among pregnant and postpartum women in urban Malawi. AIDS 1998, 12: 197-203.
• Taha, T.E., Biggar, R.J., Broadhead, R.L., Mtimavalye, L.A.R., Justesen, A., Liomba, G., Chiphangwi, J.D., Miotti, P.G. Effect of cleaning the birth canal with an antiseptic solution on maternal and newborn morbidity and mortality: clinical trial. British Medical Journal 1997, 315:216-219.
• Biggar RJ, Miles W, Miotti PG, Taha TE, Butcher A, Spadero J, Waters D. Blood collection on filter paper: a practical approach to sample collection for large epidemiologic studies. Journal Acquired Immune Deficiency Syndrome and Human Retrovirology 1997, 14:368-373.
• Biggar, R.J., Miotti, P.G., Taha, T. E., Mtimavalye, L.A., Broadhead, R.L., Justesen, A., Yellin, F., Liomba, G., Miley, W., Waters, D., Chiphangwi, J.D., Goedert, J.J. Perinatal intervention trial in Africa: effect of a birth canal cleansing intervention to prevent HIV transmission. Lancet 1996, 347:1647-1650.
• Taha, T.E., Canner, J.K., Chiphangwi, J.D., Dallabetta, G.A., Yang, L., Mtimavalye, L.A.R., Miotti, P.G. Lack of association between reported condom use and rates of sexually transmitted diseases in Malawi. AIDS 1996, 10:207-212.
• Taha, T.E., Miotti, P. G., Liomba, G., Dallabetta, G.A., Chiphangwi, J.D. HIV, maternal death and child survival in Africa. AIDS 1996, 10:111-112.
• Taha, T. E. Comparison of reported and confirmed malaria during pregnancy: findings from hospital and community studies in Sudan. East African Medical Journal 1996, 73:571-574.
• Taha, T.E., Dallabetta, G.A., Canner, J.K., Chiphangwi, J.D., Liomba, G., Hoover, D.R., Miotti, P.G. The effect of Human immunodeficiency virus infection on birthweight and Infant and child mortality in Malawi. International Journal of Epidemiology 1995, 24:1022-1029.
• Taha, T.E., Canner, J.K., Dallabetta, G.A., Chiphangwi, J.D., Liomba, G., Wangel, A-M., Saah, A. J., Miotti, P.G. Childhood malaria parasitemia and human immunodeficiency virus infection in Malawi. Transactions of the Royal Society of Tropical Medicine and Hygiene 1994, 88: 164-165.
• Taha, T.E., Gray, R.H., Abdelwahab, M.M., Abdelhafeez, A.R., Abdelsalam, A.B. Levels and determinants of perinatal mortality in central Sudan. International Journal of Gynecology and Obstetrics 1994, 45:109-115.
• Taha, T.E., Gray, R.H., Mohamedani, A.A. Malaria and low birth weight in Central Sudan. The American Journal of Epidemiology 1993, 138:318-325.
• Taha, T.E., Gray, R.H. Malaria and perinatal mortality in Central Sudan. The American Journal of Epidemiology 1993, 138:563-568.

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